Ghost rules. Really, I couldn't live without it.
I review software for a living, so I am CONSTANTLY backing up, installing new software, playing with it, and then Ghost-ing back to the pre-install state. I also Ghost my systems every few weeks so that, if something happens like a virus, a crash, or whatever, I can go back a few weeks and be back where I was. This is also handy before installing new hardware or perforing a Microsoft critial update.
The easiest and fastest way to use it is to install a second hard drive in your PC for nothing but ghost images. You then boot off the ghost floppy, spend 30 seconds pressing keys, and you're off!
Another good way is with an external USB2 hard drive. Just plug it in, boot from the floppy, and go.
Ghost also recognizes burnable optical media. You can just insert blank CDs or DVDs into your burner and it will automatically write to the disks and prompt you for the next one. This takes longer, but it works great.
Finally, you can also tell ghost to break up the image files into, say 650 meg chuncks, and it will name them in series on your hard drive, and then you can manually burn them with Nero (or whatever turns you on).
I can honestly say thta Ghost makes my life 20 times easier, and I sleep better at night that my systems are backed up easily.
-Llama