It appears that the link between hops 3 and 4 is flaky, or hop 4 is over subscribed and is dropping packets. In either case, it's a problem with Comcast. It is very likely that they already know about it. If you're lucky, it is a bad card in a router and they'll have it fixed soon. If you're unlucky, it's a saturated link and it will get fixed this quarter, maybe.