By the time this thing is possibly being tested there are going to be a few hundred Airbuses buzzing around. So, it's going to be a tough one.
For neither you'll need to completely redesign an airfield though, rather think of it as building or modyfying a terminal to receive those. I mean the batch of passengers is about the load of 2 Jumbo's which is nothing unhandlable.
Maybe we'll be riding those biggies on intercontinental flights in 10 years. I hope so