Scenario #1:
Your in the hanger and get word of bombers (mix bag 17's and 24's) inbound to your base, approx alt 15-20k approx range 20 miles. What do you up?
109K4s the only thing that can climb fast enough. Spit14 probably also, but doesn't have the 30mm for better killing, doesn't have 10 mins WEP. 109G14 with gondies also works (climbs worse)
Scenario #2:
Your in the hanger and you see the bombers pop up on your radar ring (12.5 miles out) and you get word they are at 8-12k alt. What do you up?
Nothing. it's already too late. They'll be over your base and bombing it in 2.5 minutes (or less). If you start climbing you'll maybe make 8k by the time they shut your field, but you'll be going slower (best climb) while they're going much faster (level top speed) so even if you get UP to them you still have to take more time to chase them. The way bombers work in this game is messed up big time, IMO.
Scenario #3:
Your on the CV and get word of inbound bombers, less than 10 miles out low alt 5k-ish. Which plane are you launching?
5K is low enough that anything with cannon will do. Heck even the 6x50cal will do, but when in doubt, C-hog to the rescue!