For grins I did that with my 42" LCD 1080p display. It's nice and big - but AH lack of real widescreen support meant that being without the trackIR was a PITA, and sitting far enough from the screen made it hard to see small details.
And to be honest, I thought a 30" display at higher resolution (3200 x1200 instead of 1920x1080) and closer is much nicer, and works better.
Still, worth playing with if you've got the time and inclination. Maybe you like it more than I did.
Diche