Yeah, I shot a 500 S&W. Not at all impressed by the ugly ill handling POS. For the price, give me a Dan Wesson 445 SuperMag (I know, not as powerful), or a Freedom Arms 454 Casull (again, not as powerful). Both shoot better due to better design. If I want a 50 caliber handgun, it'll be a Linebaugh or a Bowen, either a 500 Linebaugh, or a 500 Linebaugh Maximum (if I can find the frame).
The 500 S&W kicks because it has the bore too far above the grip. That's why it's as ugly as homemade sin, too.
And my Dan Wesson 44 Magnum with hard cast or jacketed 300 grain bullets will go all the way through a bowling pin. Or a 6x6 piece of cured oak.