Another semi-related work in progress is
SENS. De Grey gave a talk on TED like Kurzweil did, it should be on the TED talks website.
Something like SENS would probably make for a more paletable transhumanist alternative to some people.
Either way, I got influenced into changing from bioengineering (towards neuroscience in general) to biochemistry (where the only pioneering work I could see was SENS), but as soon as I'm back in North America I'll drop everything to get into neuroinformatics research. It's going to be the work of my life.
I can't wait.