Running a GTX280i SLI configuration here, there is no problem managing all GFX settings in the nVidia control panel. To force Vsync is a must to get smooth and good image quality imo. Running at a monstrous resolution of 2560x1600 with 16x aa it still max out at 60 fps. It will never, under any circumstance, go below 30 fps unless I'm recording FRAPS while running the game.
Built this system for max performance in AH and I have no complaints so far.
Corsair PowerSupply (PSU) 1000W HX ATX 2.2 - The most important component imo. System reliability is directly connected to the PSU.
Intel Core 2 Quad Q6600 2.4 GHz 1066 FSB - Next component to be upgraded.
XFX ATX nForce 780i
XFX GTX280i 1 GB RAM - dual-SLI setup giving a total of 2 GB GFX RAM
4 GB Corsair XMS2 Xtreme DDR2 XMS2-6400 800MHz
Creative SoundBlaster X-Fi Xtreme Music
Samsung SATAII 1TB
Seagate SATAII 1.5TB
Pioneer Blu-Ray / DVD BDC-S02BK
Lian Li PC-P80 ArmorSuit
Creative Gigaworks S750 - 7.1 surround system THX certified
Sennheiser Headset PC-160 SK-Gaming limited edition
Samsung SyncMaster 305T Plus 30" LCD 2560x1600 native resolution
Saitex X52 Pro
TrackIR 4 Pro + TrackClip
Razer Lycosa Gaming Keyboard
Logitech G5 Laser Mouse
Vista Home Premium 32-bit