NOD32 is great, seemed flawless till recently it failed to recognize (in a deep scan of all drives and memory) a W32.crypto virus infection on my pc. Only when the virus had spread and tried to access the internet and when the apps it had infected (notepad, opera, and other common apps) tried to run did it detect it. Apparently this is a common problem, as it also gives false positives for legit cryptographic applications.
Here's a line you can type in the "Run..." dialog (in the start menu) to restore task manager in a hurry though, if you ever need to. I've used it before, but I don't know if restoring task manager is all it does, so you may want to wait till one of the pros on the forum replies that it's safe to use.
REG add HKCU\Software\Microsoft\Windows\CurrentVersion\Policies\System /v DisableTaskMgr /t REG_DWORD /d 0 /f
Use at your own risk..