As a practicing Internal Medicine doc (same specialty as House), I honestly can't stand the show. Drives me nuts that they have the guy jump to conclusions before there's any information to go on....It'd be like having your CSI tech walk up to the scene, glance at it, and name the suspect without bothering to collect the evidence.
In the few episodes I've seen, about the only thing that rings true is the way the guy will sometimes sit the team down and brainstorm the differential diagnosis. What's supposed to happen then is that you order the right tests to discriminate between the likely choices, and you work your way to the right answer.
What House does isn't brilliance...it's called "premature closure" in the business. By making up your mind too early you start missing conflicting information, and you can really scr@# things up for your patient in short order.
But, it's TV, and I've got colleagues who really like it. Just does the fingernails-on-chalkboard thing to me...