Video cards (for the most part) use 16 lanes, not one lane, of the PCI-E bus. In this case, it is one interrupt per 2 bytes per clock cycle, instead of one interrupt per 8 clock cycles (1 byte).
So far, all the sound cards I have seen using the PCI-E bus, have used only one lane.
The hardware to implement PCI-E is much cheaper than PCI is.