My snippy answer is that we can best kill it by never allowing it in the game
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However, speculating how best to kill a plane that doesn't exist in the plane set is a bit difficult. We don't yet know if the remote control nature of the gunners stations (other than the tail) are modelled so we don't know with what ease or difficulty the gunners will be under in trying to defend. Even if they have all the guns stripped out, ala Le May's mods to the Tinian/Saipan bombers, they are going to be tough to catch with most of the planes in the current plane set.