They'll have to handicap it in some way to keep from killing the game.
Me 262 didn't kill the game either... the secret is called: Perk Points.
As Yeager said: at low alts they will get killed much like other bombers. If they fly at 25k, they have to climb for 45 to 60 minutes AND flying a perk plane ensures that most will try to take their time to land their bird. All that is time consuming. A noe horde of 110s is often way more effective.
And do not overestimate the number of players having 20k buff perks. It's only a small fraction.
The first tour will see B-29 mayhem everywhere for sure... but it will settle down.