The first day of the mossie 16, I upped a Ta-152 to 25k and then waited, shot down and killed a flight of mossie 16s. That guy did not have a chance. A perkless single B-17 would have stood a better chance. The man probably lost 120 perkies to what, the exhillaration of speed? Juice....Squeeze.
He also wasn't paying attention. You are in a Mossie 16 or Ar234 and see an enemy dar bar ahead, you change your route. The Ta152 is one of the best Mossie 16 killers in the game, but it takes it a long time to run down a Mossie 16 in a tail chase if the Mossie isn't cooperative.
The one Mossie 16 sortie I did was at 28,000ft, no enemy got close to me though a couple tried.