B4 for some cases you can just not use that... But you always run the risk of cross-inputting controls (hard to ONLY use elevator, not aileron) and some cases you cannot do this, like missing a wingtip.
Most bombers will not fly missing a wingtip. I'm not sure if it's right because when lightly loaded or after bombs drop you would think it has enough lift to spare. The only one I did was a B-25H where a wirble got my wingtip. I was oriented such and had just enough speed that I could nose up, full rudder, level just enough to pop flaps and gear and land right there. It was a rare moment as I've never been able to repeat it. I taxied in to land safely.