Mainly depends on what you use your system for outside of gaming. I do an awful lot of video transcoding these days, and now the time I spend in 3D Studio has just increased again. When it comes to Adobe (specifically Premiere Pro) the list of AMD GPUs that are supported for hardware acceleration includes only two cards, while Nvidia has a significant advantage (last count exceeded two dozen). CPUs from Intel add to the advantage by offering significant video transcoding acceleration (specific to individual CPUs). Last I heard AMD was lagging in that department.
The majority of students in my 3D Animation class (3D Studio) were using AMD, while I and a few others use Intel. For whatever reason they (AMD users) were reporting a lot of 3D Studio crashes, while I had two crashes all year. The first involved a Boolean operation where I subtracted more than 200 primitives from the body of a larger 'sculpted' primitive (I had been warned to avoid doing that), and the other crash involved changing a complex animated texture during a render. The second attempt succeeded on both operations. It's not very scientific confirmation, but it's enough for me to accept Intel as the better choice.
