Never Two Without Three... Heat.
As Fugi said, clean the inlets, fans and screens. If your case is equipped with dust filters, take them off for thorough cleaning. Don't forget to de-dust the Power Supply! Canned air comes in handy, but don't let it spin the fans too much. It's also a good idea to unplug the fans for cleaning since the airflow will make them act as wind turbines, feeding electricity to the motherboard instead of taking it.