"Throttling" is how the CPU controls overheating. When you reach a certain temp it starts "throttling" your CPU cycles (read throttling here like CHOKING). It skips a cycle, then starts skipping more cycles, effectively cutting your CPU speed. Since it skips every other cycle, or maybe even a couple of cycles, some things can get lost in the queue. Especially if the motherboard is heating up too, RAM is very sensitive to heat.
Disabling the throttling is fine, but make sure you arent about to have some very expensive repairs because of it. Check your temps.