It's amazing how fast we can get used to almost anything. I use my old 24" monitor at our meetings twice a year, at home I have this 30" with a higher resolution. The only noticeable issue is that I have to change the video settings and the locations for radio screens when swapping monitors. Well, my numerous desktop icons also change location but that's not a biggie. In a few hours everything feels familiar and normal. Of course in my case it helps that the two monitors have the same pixel size which makes text and icons appear in the same size on the screen. The image quality and colour temperature also look similar and the refresh rate is the same. I don't know by experience how it would feel to return from 144 Hz to 60, that might make a difference especially for an active gamer. In desktop use that doesn't make any difference.