I think we're missing the point here: the A380 is the largest civil airliner.Aside for the AN225, but how many of those are flying?!?!?
the A380 is a radical improvement over all current airlines.
Boein's latest model, the 787, although it has inovative features, is not the biggest, nor the fastest, nor the longest range airliner. It is touted as "20%" more efficient than comparable airlines , but that's pretty vague.
And...it hasn't flown yet.
The A380 is a historic plane marking a new era in transportation. Can you say the same thing about the 787?
I believe the lead in commercial aircraft design has been taken by Airbus.