I recently got a mini-iPod on April 9. It took me about an hour to get it out of the box, load the software, hook up the USB, figure out how the directory and file structure worked, load songs into the software, download songs, and start playing them. Yes, iTunes is the software that it uses. Other than iTunes wanting (quite persistently) to be the default mp3 player, it seems like good software. The version of iTunes I have is 4.7.1.30 (HP) for Windows XP.
This is the only portable MP3 player I have ever owned. I read about a bunch before buying a mini- iPod. There are plenty of reviews (actually a few too many) for the various players. I choose Apple because every Apple product I ever had was simple, reliable, and easy to maintain. The mini-iPod is no different.
Frequently Apple products (computers) are 2-3 times more expensive than their competitors. Not so with the iPod, so it was a pretty easy decision for me. Good luck.
Regards,
Malta