What i do, is the second i hit the runway i hit backspace, after that there is no need to touch it again.
You will then be selected on wing bombs, if fighters intercept you, you can drop wing bombs and get better handeling,weight and speed. Not to mention if will help you pull g's... too many g's and your wing's will rip off.
I have made the mistake of droping internal, and pulling out hard, the x4 1k worth of bombs will make your wings snap off under 2g's if you have 50% fule and are going over 200mph.
So, proceed with caution, always drop the wing bombs first.