TIR was a steep learning curve for me.
I bought it after some 10 years of playing AH using POV hat and going to bed at night with my thumb throbbing from all the working the coolie.
I spent a good month trying every sort of configuration I could think of. I almost gave it up. Then I read Mace's description of the "dead zone" issue (my biggest problem) and after I started using his profile things started to get more natural. At first, I hated Mace's profile because it gave me that "sitting on a ball" feeling which felt really unstable to me. I forced myself to stick with it and after about a week things just sort of slipped into gear. Now (some two years later), it is as natural for me as can be. I love it! I would NEVER go back to the coolie hat!
The most recent (about two months ago) mod I've made to my HOTAS setup was to assign the "pinky button" (CH FighterStick) as a macro command that I call my "Gunnery button". Here's what it does:
1. Holds the forward view button (KB8). Mace talks about the effect of this in his doc. It locks the forward view but allows the side-to-side, up/down, and in/out views to work. Great for setting up for gunnery.
2. Turns on Zoom. Whatever zoom setting you previously used will be in effect. I also have a HAT on my Pro Throttle assigned to changing the zoom setting so I can zoom in and out while I hold the pinky button in.
3. Centers TIR. Now that the forward view button is being held and Zoom Mode is on, the TIR is centered so that my view is straight down the gunsite and I'm all set for firing.
When I press and hold the pinky button, the macro performs the three steps just mentioned. When I release the pinky button, the forward view button is released and Zoom Mode is turned off. This allows me to very quickly return to maneuvering. When I want to quickly get back to "guns ready", I simply press and hold the pinky button again. It's really worked out great.