Seeker, wind does have an effect on range. A 300mph headwind will drastically shorten the range, while a 300mph tail wind will give you a nice extention on max range. A headwind can and will screw with accuracy, but the tail wind doesn't; in fact it gives you a tad better accuracy. As long as you're firing straight back anyway. Shoot off to one side and the "curveball" effect will screw things up.
Here's what happens in the "curveball effect" so grab a pen. No, not for taking notes but rather as an easy demo tool. You fire a bullet into a 90° cross-wind. Bullets spin to the right from the right-hand twist of the rifling. The wind impacts the right side, where the bullet actually grips the air. Put the tip of your pen on your finger and spin it in place to the right. Now if a wind hit the pen, the pen would grip the air and force it downwards from the spin. As a result, the pen would generate more lift and climb. But since bullets aren't perfect cylinders, lift isn't generated evenly. So the front-end of your pen would come up, throwing the "bullet" into a pretty weird cork-screw. It would go high and right.
The exact opposite would happen if the wind hit the left side of our "bullet". Wind would hit the bullet, be deflected upwards by the rotation, and send the bullet into a slight dive. Since the nose-end is heavier than the ass-end, it would veer off to the right at the same time.
Forgive my horrid drawing ability, but here's a simple graphic showing the effect:
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Flakbait [Delta6]
Delta Six's Flight SchoolPut the P-61B in Aces High"I wanted to go back for another 50 missions, but they ruled it out
because I had a case of malaria that kept recurring. So I had to stay
in the States and teach combat flying. I was shot down by a mosquito!"
Frank Hurlbut, P-38 pilot 
