Did you say you've tried older drivers for the GPU? When doing so did you make sure to delete the installed drivers before installing others? Have you tried running a driver cleaner before installing different drivers?
I used the stock drivers first that came with the card, then removed them, ran driver cleaner, installed newest.
I think everyone can understand, that I'm getting a bit tired of all this stuff.
If the just the game wouldn't lock-up would compatibility mode - everything would be fine, because apart form that, it runs like charm