For South Park absolutely NOTHING is sacred, they make fun of it all.
God, Devil, Jesus, Jews, Bin Laden, they all get nailed.
If you can accept that, wrap your head around it. Then often SP has some quite interesting things to say.
If you can't, they'll step on your @$#% slam your !@#$! and #$^%#$^ down your !#@$@#$!
Personally I decided some 4 years ago they were tired of doing SP. And they had figured out that the only way they could quit, was if they got shut down in a lawsuit. So since that day they have been trying harder and harder to incite that lawsuit. So far it seems to be failing. But then I'm not sure just how "bright" those 2 really are.