Not really, takes a lot of spraying to make your hits count. 1 50mm should knock the wing or tail off at 800yds.
Yeah with Mk108s however a good Head on pass from 10 or 2 can yield 3 bombers in one pass if done correctly, problem is you lose speed slamming rudder like that each time.
Can't remember which FSO but was an 8th AF scenario ended up with 8-9 buff kills on one pass before a 47 bounced me.
Then again this was looooooong time ago