I'm a big EMG fan. As soon as I buy a guitar, the first thing I do is replace the stock pickups with EMG actives. Seymour Duncans run a close second, but in my opinion you get more range and tone out of EMGs.
If you haven't replaced pickups before by yourself, just let the local shop do it for you. It's not rocket science, but you don't want to mess it up. Most shops will let you watch them do it, so you get a general idea of what to do next time. I'd suggest getting an old, beat up guitar, and practice removing and installing the current pickups to get a feel for what to do. It's not difficult, but the more info and practice you have going into the replacement, the better.