Not to get to technical here, running a CPU clocked higher than the factory clocked settings even if your CPU came unlocked so it is capable of being overclocked
Opens the door for the "high resolution timer for each core", to become unstable and hence AMD's provided work around to engage, when the timers fall out of sync with each other...the timer tolerance is very close to something like "1 tic or lesser" going from my aging memory
Hope this helps
TC