If you had a squadron of those being flown remotely with 1-3 human piloted aircraft as a last measure against a target. Then you could swamp the zone with them to get one or two into the target with a high destructive payload. The losses would be much cheaper. The human piloted aircraft standing off then could launch things like cruise missiles or other smart munition as a second wave to swamp the zone if the unmanned were wiped out.
The premise of the automated assembly line running all the time seems like an industry trying to PR the idea of keeping themselves in business for a long time. Small, fast\maneuverable, and cheap, so you can flood the combat zone with them. Sounds too good to be true. You could stuff aircraft carriers full of them, then sit in the middle of the Med and Indian ocean, or closer to hot spots and shut down the airspace and ground vehicle movements with hoards of them that constantly cycle out with fresh hoards to refuel and rearm.
The answer in animation series was to carry a hoard of tiny munitions designed specifically to intercept the hoard of unmanned weapons. Or you have something that comes in at very high alt, looks down, and identifies the hoard and lunches munitions to target the hoard before your hoard enters the zone. Wonder how much collateral damage you would get after your hoard killing munitions destroy the unmanned hoard over it's home country as all the debree and unexploded ordinance starts landing on the ground.
If these things have really good stealth technology, just run them NOE where humans don't expect to see a hoard of fighter type aircraft, then they popup under the defenses, swamp the zone with no worry about losses. If you have enough of them and the factory back home is pumping them out 24x7, just keep running in waves.