In real life 109s were left in full auto, in FB its perfectly reasonable (and "real") to fly 109s in full auto.
In fact there are several interviews of 109 pilots where they were asked directly about manual vrs auto and the consensus was that full auto was correct. There’s no mixture control need for the 109s because they are fuel injected. The only time you need to manually use radiators is to keep speed (closed) or if you are running hot. 90% of the time leaving them in auto is fine.
A common feature of the German fighter engine controls (post ‘42) was the single lever operation (engine and the propeller function to one control lever). The DB, Jumo and BMW systems were different in detail but they controlled the engine and propeller etc…. The pilot basically moved the "Throttle" to adjust the power at all speeds and altitudes. These “automatic” systems adjusted the mixture, ignition timing, supercharger speed, manifold pressure, engine speed (via prop pitch) and even MW50/GM1. Each version of these engines had their own particular set-up and variations.
It’s a myth that in FB you need to be at idle to "activate MW50" (and C3 injection on the 190s; "erhöhte Notleistung"). MW50 injection was armed by flipping a switch on the dashboard. Injection was only activated, though, when the throttle was advanced to the stop.
That means MW50 was only injected once war emergency power was reached, at full boost, at full rpm. The resulting power setting was called "special" war emergency power to discern it from emergency power without additional injection. Also MW50 is only of real benefit (besides charge cooling) below supercharger critical alt. So you would just turn it off. One thing to remember those is MW50 will run out so if arent paying attention in FB you could destroy your eng by running at max power to long.
So in FB you can "activate" MW50 at any point under 100% throttle with no ill effects.
Its not as difficult as it sounds, aircraft were designed for simple operation. The Fighter pilots needed their attention elsewhere, like fighting
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Just learn how to navigate and you will be fine. In DF servers you radio compass will always point to you "home base", in coops etc its points to the "next waypoint". Just follow where it points you and you will have np.