Morph,
Your avatar is giving me a headache...
Personally, I believe velocity ruins more meat than bullet diameter or sectional density.
Cowboy at our camp several years back used to hunt whitetails with 300 Winchester Magnum handloaded with 130 grain hollowpoints. That slug had to be traveling dem near 4000 fps. The meat damage it caused on a small four-point buck was horrendous...both sets of ribs, off front shoulder, backstrap and part of ham were useless.
That kind of performance isn't needed. A 180 grain slug would have been far preferable.
Regards, Shuckins/Leggern