Lower trustline also means the engine profile will be more symmetrical. Since a/c fusalages are usually wider at the bottom than on the top. if you have the engine wide parts down, too, you can more easily do a symmetrical, pointy nose. If you look at the nose sections, it`s quite striking that inverted-Vee engined planes have a pointy, bulletlike nose, whereas the normal Vee engines always have one kind of a ship-bow, curving upwards, which is more disturbing to the airflow.