No, it does not matter, but there were far fewer PR aircraft used.
The bigger problem is that the 533 number does not diferentiate how they were lost.
A Mosquito that returned to base and had to be written off does not count as a kill, but it does count as a loss.
Referencing the two tables I posted wee can see that:
In 26,939 sorties there were 88 Mosquito's written off after they returned. In the same time there were 108 that failed to return.
In 39,795 sorties there were 254 that failed to return and that includes the 108 from the 26,939 nightime sorties. So we know about 342 losses just from those totals. In the 12,856 sortie difference there were surely some that also were written off after returning. If the ratio was roughly the same that would be another 42 airframes for a total of 384. Given that those 12,856 sorties were during daylight and the loss ratio on them was much higher it is probable that a likewise disproportionate number were damaged and had to be written off. Then there are training accidents, PR aircraft that failed to return and PR aircraft that had to be written off after returning.
26,939 night sorties = 108 failed to return. 0.4% loss rate
12,856 daylight sorties = 146 failed to return. 1.14% loss rate
Some of those losses would also be due to flak and not fighters.