mine are Fix it utilities (Trend micro AV) , adaware , hijack this, along with the firefox browser .
Hijack this is a user beware program but its alot easier then doing the registry manually .
I only find about one cookie per week these days w/adaware.
i also check my running proccesses and keep those to a min also .
the other thing that helps is a registry defrag .. (i never do a hd defrag just the reg )
theres lots of other spyware programs to be had, but ive had good luck w/ my setup so far (havent had a successfull virous in a very long time)
the temp files/main windows folder is were alot of bad stuff can hide , ive been cleaning all my neibors pc's for them, so ive kinda got bug extermination down .