Rex Barber shot down Yamamoto's Betty with a P-38G in April 1943.
The first two operational U.S. fighter groups in the 8th AF to go all the way on deep penetration raids escorting bombers were the 20th and 55th, flying P-38H's.
The first U.S. fighters over Berlin were P-38H's and P-38J's of the 20th and 55th fighter groups.
The two top U.S. aces of al time, Major Richard Ira Bong with 40, and Major Thomas B. McGuire with 38, flew P-38H's, P-38J's, and P-38L's.
The first fighters to fly from the U.S. to Europe (Operation Bolero) were P-38F's.
The list is endless.