The "+" and "-" keys control prop pitch, which translates to changes in RPM (the RPM gauge is a measure of prop RPM, not engine).
When you change the prop RPM, there is an effect on engine manifold pressure as the workload decreases/increases. Increased pitch = increase workload and vice-versa. As you reduce prop RPM, the max engine manifold pressure will drop with it, so you see 'both' settings move.
To set a specific engine config (like Max Cruise) first set the RPM, then make final adjustments to your manifold pressure (throttle).
Hope this clears it up a bit!