No luck deleting the controllers, I even uninstalled all the software and started over. \
Also it is my understanding that USB devices aren't "calibrated" per se it's differnt.
Also USB ports normaly are powered and will power off when not being used so you will lose "calibration" when the port wakes up again, simply moving your controls to thier limits "re-calibrates" them. Finally, if this is the case, some calibration issue, then how/why would I have the same issue when the joysticks are uninstalled and unplugged? I'm really at a loss here, Note I did have the mouse set to fly a couple times and same effect. Remember in the joystick setup screen, where you choose axis and effect, those numbers properly reflect joystick /throttle/ and rudder position and aren't jumping around.
Maybe it is just a general hardware issue Motherboard USB port driver or some such?