Well,
Considering that the P-47 was an evolutionary developement of the earlier Seversky P-35, P-41, and Republic P-43 fighters, the sweeping changes that you are proposing would have been just about impossible from a manufacturing point of view.
Seversky (later Republic) designed and built their aircraft using technology and techniques that while outdated from a hindsighted point of view, used quite familiar and proven solutions to them.
Also consider that most cutting-edge military technologies and manufacturing techniques were, and still are proprietary and highly secret, and most military aircraft manufacturers of the time were competing with one another for contracts, and were very reluctant to share ideas.
The changes you are proposing would have required almost a complete re-design of the entire airframe, not just the wing structure, and even if the designers had chosen to use the same basic external shapes, the inside structures would not have been those of a P-47. This would have meant delays due to sub-contracting for new components and assemblies.
In addition, the changes would have meant shutting down the existing plants to re-tool, or even the construction of new plant space. More delays.
The changeover would also have required the production of expensive new manufacturing jigs and tooling under wartime conditions of shortages...not an easy thing to do, and probably would have meant even more delays.
After the plants were built, you would have to either transfer existing plant workers or train new workers to man them. Slowing current production and adding more delays.
Finally, after all that expenditure of capital, time, and effort, what do you have...an unproven design using new, unproven technologies, and probably costing much more than further evolutionary developement of the existing P-47 airframe design would have provided (P-47N).
As far as armament goes, those decisions were made and specified by the military, not the manufacturers. Also the weapons themselves were supplied by the military, often after the delivery of the aircraft, and not by the manufacturer.
I'm sure many firms would have been more than happy to provide the Armed Forces with aircraft designed to mount multiple 20mm canon, but the U.S. Military in 1943 was quite happy with an armament of four, six, or eight .50 cal machineguns, of which they had plenty, and which cost much less to build than licensed Hispano-Suizas or Oerlikons.
Wishful thinking I'm afraid.
CptA