Just as an FYI, here are some problems with the shuttle:
1. The SRBs mean that the first 2.5 minutes of flight are unsurvivable if anything bad happens if staying on until SRB burnout is not an option. Even if the Challenger crew had been told "Guys, we picked up a burnthrough, you need to get out of there" there would have been _nothing_ they could have done.
2. The design is the result of multiple compromises. The Air Force was pushed into agreeing to use it as their sole launcher, so the cargo requirement was more than doubled over Maxime studmuffinet's original design. Their crossrange requirements required the change to the big delta wings too. These add weight and complexity and made the situation that led to the Columbia's destruction over Texas.
3. The engines are super hopped up, kinda like a Honda Civic pushing out 500hp versus a 454 in the same situation. Sure, you can do it, but you're running things real hard and you need to rebuild it after moderate use. The SSME is the Civic, and the F-1 from the Saturn V is the 454. These engines need to be rebuilt all the time, and they're super high strung.
This plus a system that's incredible complex mechanically.... it's a marvel that there have only been two accidents. Well, a marvel that's been helped by the crew of 10,000 people that support it.