Rich,you can use sst and game settings together,it's not a matter of either,or. You dont need to delete any settings,just be sure to select the profile you want to use.
I have found that I use some of the sst and most of ingame settings,example,I use sst to assign hatswitch to 4 or 8,then use ingame settings to assign the functions to the switch or button.
If your ever in TA look me up,I'll be glad to help if I can. BTW my ingame ID is the same as here.