If it's integrated audio, think about it.
Integrated - Costs somewhere around $.02 to manufacture. (Not kidding) Uses the system RAM. Uses the system CPU. Reserves extra unusable space on the CPU "just in case."
Slot cards - Costs somewhere around $30-$50 to manufacture. Uses it's own RAM. Uses it's own CPU.
I've had this Sound Blaster Audigy 2 ZS in this gaming machine for four years. Hasn't failed me yet.
EDIT: I'd like to note that if we're talking about the same card, it has a FireWire port on the back, not a gameport.....although, I think it has a game port extension thing that uses another PCI bay? Be careful with that. I think I tried using it a long time ago and the system wouldn't boot. I suspect the power supply, but still.