The thing with the CH quadrant is that it's tall. If you can mount it LOWER it will be way more comfortable. At first this turned me off for a couple of weeks. I almost gave up, then inspiration kicked in.
I had removed a keyboard tray from my desk, as I don't like them and don't use them. After yanking off the tray-stop front edge, it was a perfect mount for the quad. It lowers the levers to the level of the desktop (this is where the stick is while I fly.
I have a slightly curved desk, and the way my seat sits my torso is angled in a bit. The red arrow is the way my torso points. The red line shows the height of the top of the desk relative to the quad.
I then found by accident that it was more comfortable to angle away from me (to the side so that my hand position was much more natural. Almost as if an extension of the arm rest itself. The other arm doesn't need this as it rests on the stick palm rest. I use the right most quad button down position as "look up" and with a bit of practice this works just as well as my old mapping (both hands on the stick). It might look a bit of a stretch, but I've got big hands and my thumb can rest on the button most of the time. It's rather simple to adjust any of the trim without shifting my hand. I can adjust from left to right roll trim, elev trim, RPM1, RPM2, throt1, and throt2. Just using my other fingers I can push or pull the levers and make adjustments as I wish without moving my hand back and forth or taking it off.
Modes 3 and 4 are mapped for 4-engine bombers.



P.S. forgive the mess I was tearing my desk up today looking for a post-it with a password.
P.P.S. I move the pedals out of the way when not in use. That's why they're at an odd angle.