Historically speaking, there were three angles that a bomber was vulnerable to. A 20º cone head-on, and directly above. Slashing attacks were nearly impossible to defeat due to the angles and speeds. Attacking from directly behind is suicidal, that's a given. But head-on attacks, with up to 7 guns on you, can't be done in AH. It should be only 5 guns, but since the ball turret can be elevated to about +5º you can fire through the aircraft with it. Known bug that still hasn't been fixed.
Lancs aren't trouble; they're flying targets. Some 30 caliber machine guns positiioned on top and on the front. A pair of 50 cals tacked on the rear, gee there's a real threat. Come at 'em from below and they're toast; aim for the wings.
B-26s are easy prey too. Above and behind or directly above are prime angles for a sure-fire kill. I vulched one guy 4 times simply by diving on him; this was done using a D-hog.
Ju-88s are easy to kill at any angle.
B-17s are impossible to kill from head-on, rear, and below. So you're stuck with slashing attacks, which work very well. In a single sortie I shot down a pair of B-17 using slashing attacks and a D-hog. 10 and 2 o'clock work best, and aim for the inboard engine. Dispersion will not only kill that engine, but maybe blow the wing off or cause a pilot-kill. Any other angle usually won't work unless you get the drop on the pilot/gunner. Attacks from above are sort of a grab bag; you might get him, he might get you. The same goes for strikes from below.
TBM-3s are also easy kills. Below and behind works, or a simple bounce from above. Again, aim for the wings to be sure of a kill.
Someone once asked me why he kept losing kills. Easy, he didn't keep shooting. If you blow an engine the guy can still ditch, but if you rip his wing off he's dead. Inflict enough damage to make sure he goes down. This means aiming for the wings or tail section. Once you've got him burning and going down all you have to worry about is someone stealing the kill. Or you can keep firing until the guy explodes, which wastes ammo in my opinion. Crutial if you drive a Yak like me.
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Flakbait [Delta6]
Delta 6's Flight SchoolPut the P-61B in Aces High"With all due respect Chaplian, I don't think God wants to hear from me right now.
I'm gonna go out there and remove one of His creations from this universe.
And when I get back I'm gonna drink a bottle of Scotch like it was Chiggy von Richthofen's blood and celebrate his death."
Col. McQueen, Space: Above and Beyond