Of any movie, cartoon or folk tale you have seen or heard or read....
(fictional of course)
... which character do you think would win the 'Greatest Evil' act award?
This is not body count or gore stuff btw.
My vote is for:

Gargamel
He found a village of 100 male smurfs... which as far as we know is their entire race ... and creates a female smurf and dumps her in their midst.
..and she doesn't like any of them.