Just to close this thread out with the end of the story, in case anyone ever has the same problem.
I got a new sound card thinking that could be the problem (Creative Sound Blaster X-Fi Titanium Fatal1ty Professional, best card that was available locally). Problem continued.
I was losing the sound anywhere from every 5 minutes to an hour. Sometimes I couldn’t even get the plane off the ground and it would quit. My vox still worked (meaning the sound card was functioning) but all the game sounds were kaput. As soon as I left the game, sound was working in Vista. Restart the game, go 5 minutes and silence. I can’t count the number of times I crashed because I couldn’t hear the buffet or wind sounds going up to compressibility.
I’d get the odd pops and pings and the sound would drop and either just quit or come back. I dropped out for about 45 minutes to let the computer cool, following a theory that somehow the card was over heating. I was just about ready to do a OS reinstall when I looked again at a piece of software that Creative makes called Alchemy. Creative ALchemy is supposed to allow you to run your favorite DirectSound3D games on Windows Vista with full hardware accelerated 3D Audio and EAX support.
I had tried it on the original sound card but it wouldn’t recognize the path to AH. On a whim, with the thought that this was a new card running on a new, different driver, I tried it again and this time it took. I popped back in to AH and flew for four hours and no quitting.
What is weird is, I’ve been using this machine for 7 months WITHOUT this piece of interim software and it has worked fine. Why it works now (or then) is a mystery, but if it works, it works.
Thanks for all the help and advice folks!