I have a CH FighterStick, CH Pro Throttle, both of which I set on a piece of finished wood (about 2' x 1' x 3/4") in my lap, about in the same position it would be if you were really flying. My CH Pro Pedals are obviously sitting in the floor.
I find this relieves the strain in my right shoulder and arm from "reaching" for the stick if I sit on the desk.