Yes, I do adjust my prop rpm and manifold pressure as needed (throttle setting) to achieve range and time on station. And we do have propeller pitch control, it's called the RPM adjustment. Mixture control is pretty simple, the settings are full rich, auto rich, auto lean and idle cutoff (for pressure carburetors). Not many consequences of misadjustment other than you'll run outta fuel too early or your engine will quit cause the mixture's too lean.
I like full immersion. I loved Falcon 4.0 SP3 and 4. Reason no online F16 sim? I think it'd be awful hard to model the online aspects of BVR and IR missles and the countermeasures....let alone modern avionics and targeting systems....You'd need a huge AI support system for in-threatre ATO's and such. Things like STT and TWS are just two modes in the look-down-shoot-down capability of the modern radar system that would be very hard to give to an airborne aircraft I would imagine. I don't mind reading a manual...I'm not a quakeaholic. I read Falcon SP3 and SP4 and had a great time....played with friends against AI and each other and had hours and hours of fun. I loved the ramp start function of the jet, it taught me how to start an F16. I like all that stuff. I learned how to use the radar modes to their best and the envelope of the jet based on factual information taken from F16 specifications and flight characteristics. It's the next best thing that I can access to actually getting in a real jet and flying it.
Oh and modern day complex, propeller driven aircraft still have a throttle, prop pitch control and mixture control....fuel injected or carbureted. Turbo supercharger waste gates still run by oil pressure and engines can still be overboosted and damaged..nothings changed in that respect since WWII.