Willing to bet in the future we will see multiple unmanned scram jet aircraft,with the ability to launch advanced missiles at targets no humans will lay eyes on,with the exceptions of a camera or two or three.
Now the day we have a missile that is stealth, no one will see it coming,and if its anything like the aim-9x..it will not matter.
Although I agree that there will be unmanned SCRAM jets, I doubt they will be for combat purposes. I understand spy/recon/bomber planes being unmanned, but fighters not as much, as then it's all money. It doesn't really matter if you shoot down a plane, a countries out a few million, yay, scoot over a monitor and they're up again... I don't really get a tactical purpose for it...
And although yes, a stealth missile would be pretty awesome, one day, stealth technology will be broken. A "new" way to detect only god-knows-what will come out, and stealth technology will be gone. Now, seems to me like if we rely on "stealth" unmanned aircraft who's main purpose is to deliver a missile here-or-there, we're screwed. But, anywho, that's my $.02
Towards the OP:
The F-35 is a beast, but it doesn't seem like it's made to operate alone. Put up a group of F-22s with some F-35s and something's gonna get blown up...
~Trig