DVI or analog? Make sure the monitor is pickingup the right input? I.e. sometimes you can choose on the monitor which mode it's receiving. Also, if both are DVI, try just plugging into the other card slot.
The other option would be failure of the card itself to run. Does it sound like windows loads properly? You get the POST beep, startup sounds, HD churns, like loading Windows?
Or does it just hang there and never boot?
Might be an incompatibility with the motherboard and the card, or a lack of power to run it. Possible, but make sure the monitor is hooked up first before you start sweating. Many a time I've upgraded a PC and had to do the guessing game of "which vid card port is primary" and "which monitor mode is analog, which is digital?" to get it right.